IVF with ICSI in Bangalore – Cost, Process & Who Needs It

IVF with ICSI

IVF with ICSI in Bangalore costs ₹1,00,000–₹1,60,000 per cycle, recommended when standard IVF fertilisation is unlikely due to male factor infertility — low sperm count, poor motility, poor morphology, azoospermia, or previous IVF fertilisation failure. At Janisthaa IVF Bangalore, ICSI is performed in our dedicated embryology lab by trained embryologists at all three centres — Malleshwaram, RR Nagar, and Basaveshwaranagar.

What Is ICSI and How Is It Different from Standard IVF?

ICSI  Intracytoplasmic Sperm Injection  is a specialised fertilisation technique used within an IVF cycle. In standard IVF, thousands of sperm are placed around a mature egg and one sperm fertilises it naturally. In ICSI, the embryologist selects a single best-quality sperm, immobilises it, loads it into a fine glass pipette, and injects it directly into the egg’s cytoplasm  bypassing the natural penetration step entirely.

This matters because natural penetration is exactly where male factor infertility causes IVF to fail. The rest of the cycle is identical in both approaches: fertilised eggs develop into embryos over 5 days, and the best-quality blastocyst is transferred to the uterus.

ICSI has been used since 1992 and is now used in approximately 70% of IVF cycles worldwide. At Janisthaa IVF Bangalore, ICSI is performed in a dedicated embryology laboratory by trained embryologists.

IVF with ICSI Cost in Bangalore 2026 -Complete Breakdown

ComponentCost (₹)Notes
Standard IVF Cycle (Base)₹80,000–₹1,20,000Includes ovarian stimulation monitoring, egg retrieval, embryo culture, and embryo transfer.
ICSI Add-on₹20,000–₹40,000Additional cost for Intracytoplasmic Sperm Injection (ICSI) to improve fertilisation.
IVF + ICSI Complete Package₹1,00,000–₹1,60,000Comprehensive package including IVF treatment with ICSI at Janisthaa IVF.
Stimulation Medications₹20,000–₹60,000Charged separately; varies depending on ovarian response and medication requirements.
Anaesthesia (Egg Retrieval)₹4,000–₹7,000Local anaesthesia with sedation during the egg retrieval procedure.
TESA Sperm Retrieval (if Azoospermia)₹15,000–₹40,000Testicular Sperm Aspiration performed on the same day as egg retrieval when required.
Embryo Freezing (Surplus Embryos)₹15,000–₹25,000Optional service for preserving additional healthy embryos for future IVF cycles.
PGT-A Genetic Testing₹30,000–₹60,000Optional preimplantation genetic testing for chromosomal screening of embryos.

Get your ICSI cost estimate at Janisthaa IVF Bangalore – free consultation with Dr. Shwetha.

Who Needs IVF with ICSI?

ICSI is recommended when:

  • Low sperm count (oligospermia) — below 5–10 million/mL, where natural IVF fertilisation is unlikely
  • Poor sperm motility (asthenospermia) — less than 20% progressive motility
  • Poor sperm morphology (teratospermia) — less than 2–4% normal forms
  • Azoospermia — zero sperm in ejaculate; sperm retrieved via TESA or PESA must be used with ICSI
  • High DNA fragmentation (DFI > 25%) — ICSI allows individual sperm selection to minimise this factor
  • Previous IVF fertilisation failure — if eggs failed to fertilise naturally in a prior cycle
  • Very few eggs retrieved — when only 2–5 mature eggs are available, ICSI maximises each opportunity
  • Frozen/thawed sperm — cryopreserved sperm (cancer patients, sperm banking) is used with ICSI

You may NOT need ICSI if: sperm count, motility, and morphology are all normal, this is a first IVF cycle with no prior fertilisation issues, and female factor is the primary cause. Standard IVF may be sufficient — Dr. Shwetha will confirm based on your specific semen analysis.

Not sure if you need ICSI or standard IVF?

Dr. Shwetha reviews your semen analysis and recommends the right approach before any treatment begins.

ICSI Success Rate in Bangalore - What to Expect by Age

StageTypical Rate
Egg Survival After ICSI Injection90–95%
Fertilisation Rate (2PN Formation)70–85% of mature eggs
Blastocyst Development Rate40–60% of fertilised eggs
Female AgeClinical Pregnancy Rate per Cycle
Under 35 years50–65%
35–37 years40–50%
38–40 years30–40%
41–42 years20–30%
Over 42 years10–20% (Donor egg IVF is often recommended to improve success rates.)

IVF with ICSI vs Standard IVF - When Does ICSI Make the Difference?

FeatureStandard IVFIVF with ICSI
Fertilisation MethodSperm fertilises the egg naturally in the laboratory dishA single sperm is injected directly into the egg
Sperm Count Needed≥1 million motile sperm/mLAny count, even 1 viable sperm may be sufficient
Best ForNormal semen analysis and female factor infertilityMale factor infertility, azoospermia, or previous IVF fertilisation failure
Fertilisation Rate50–70% of eggs70–85% of eggs
Cost at Janisthaa IVF₹80,000–₹1,20,000 per cycle₹1,00,000–₹1,60,000 per cycle
Can Use Surgically Retrieved Sperm?NoYes (TESA/PESA)

ICSI makes the most difference precisely where standard IVF would otherwise fail at the fertilisation step  male factor cases. For pure female-factor infertility with normal sperm, standard IVF fertilisation rates are already comparable, so ICSI’s main benefit there is marginal and not always worth the added cost.

ICSI with PESA - For Men with Obstructive Azoospermia

PESA (Percutaneous Epididymal Sperm Aspiration) retrieves sperm from the epididymis — used specifically for obstructive azoospermia where a blockage prevents sperm from reaching the ejaculate. PESA is less invasive than TESA and is typically the first-line option when the cause is a confirmed blockage rather than a production issue.

Diagnosed with azoospermia? Zero sperm doesn’t mean zero options.

TESA/PESA + ICSI has helped many couples at Janisthaa IVF achieve biological parenthood.

What Happens During the ICSI Procedure - Step by Step

  1. Ovarian Stimulation (Days 1–12): Daily hormone injections stimulate multiple follicle development, monitored every 2–3 days.
  2. Egg Retrieval: When follicles reach 18–20mm, a trigger injection is given and eggs are collected 35–36 hours later under sedation. Male partner provides a semen sample same day (or TESA/PESA sperm is used).
  3. Sperm Preparation: The sample is processed using density gradient centrifugation to isolate the best-quality motile sperm.
  4. ICSI Fertilisation: Under a micromanipulation microscope, the embryologist selects a single normal, motile sperm, immobilises it, and injects it directly into each mature egg’s cytoplasm. Takes 10–15 minutes per batch.
  5. Fertilisation Check (Day 1): Injected eggs are checked the following morning for successful fertilisation (2PN formation).
  6. Embryo Culture (Days 1–5): Fertilised eggs are cultured until they reach blastocyst stage — the highest-implantation-potential stage.
  7. Embryo Transfer: The best-quality blastocyst is transferred via a fine catheter under ultrasound guidance — a 10-minute procedure requiring no anaesthesia.
  8. Pregnancy Test: A beta-hCG blood test 10–12 days after transfer confirms pregnancy, with a repeat test 48 hours later to confirm appropriate doubling.

Janisthaa IVF's ICSI Lab - What Makes Ours Different

ICSI is performed in our dedicated embryology laboratory at all three Bangalore centres, by trained embryologists using micromanipulation equipment specifically calibrated for sperm injection precision. We also offer IMSI (Intracytoplasmic Morphologically Selected Sperm Injection) — an enhanced version of ICSI examining sperm at 6,000× magnification versus the standard 400×, used for high DNA fragmentation, repeated ICSI fertilisation failure, or severe teratospermia.

Every couple receives a full written, itemised cost estimate before treatment begins — there are no mid-cycle surprises at Janisthaa IVF.

Frequently Asked Questions - ICSI Cost Bangalore

How much does ICSI cost in Bangalore?

IVF with ICSI costs ₹1,00,000–₹1,60,000 per cycle at Janisthaa IVF Bangalore, including stimulation monitoring, egg retrieval, ICSI fertilisation, embryo culture, and transfer. Stimulation medications (₹20,000–₹60,000) are additional. If TESA sperm retrieval is needed, add ₹15,000–₹40,000.

What is the difference between IVF and ICSI?

In standard IVF, sperm fertilises the egg naturally in a lab dish. In ICSI, a single sperm is selected and injected directly into the egg. ICSI is used when natural fertilisation is unlikely due to male factor infertility. Both approaches use identical stimulation, retrieval, and transfer steps — only the fertilisation method differs.

Who needs ICSI instead of standard IVF?

ICSI is recommended for low sperm count (below 5–10M/mL), poor motility or morphology, azoospermia (with TESA/PESA), high DNA fragmentation, previous IVF fertilisation failure, and when very few eggs are retrieved. Men with normal semen analysis in a first IVF cycle may not need ICSI.

What is the ICSI success rate in Bangalore?

ICSI fertilisation rates at Janisthaa IVF are 70–85% per mature egg. Clinical pregnancy rates per cycle by age: under 35: 50–65%; 35–37: 40–50%; 38–40: 30–40%; 41–42: 20–30%.

Is ICSI painful?

The ICSI injection is performed on eggs in the lab — not on the patient. Egg retrieval is done under sedation, so there is no discomfort during the procedure itself. Mild bloating and soreness after retrieval are normal.

Can ICSI be done with TESA sperm for azoospermia?

Yes. ICSI is always used with surgically retrieved sperm from TESA or PESA. Retrieval is performed the same day as egg retrieval, and the embryologist uses the sperm immediately for ICSI. Many men with azoospermia have achieved biological fatherhood through TESA + ICSI at Janisthaa IVF Bangalore.

Is ICSI safe? Does it increase birth defect risk?

ICSI has been used since 1992 with millions of healthy children born through this technique. The absolute risk of birth defects is not significantly different from standard IVF. A slightly higher rate of sex chromosome abnormalities (0.8–1% vs 0.2%) appears related to the underlying infertility condition rather than ICSI itself.

Where can I get IVF with ICSI in Bangalore?

ICSI is available at all three Janisthaa IVF centres — Malleshwaram (15th Cross, 8th Main Rd), RR Nagar (BEML Layout, 1st Main Rd), and Basaveshwaranagar (2nd Block, 1st Main Rd). Call +91 95911 11407 or WhatsApp +91 90356 81163 for same-week appointments.

Book Your ICSI Consultation at Janisthaa IVF - 3 Bangalore Centres

CentreAddressContact
Basaveshwaranagar (Main)2nd Block, No. 2, 1st Main Road, Basaveshwaranagar, Bengaluru – 560079+91 95911 11407
RR NagarNo. 1601, 1st Main Road, BEML Layout, RR Nagar, Bengaluru – 560098+91 90356 81162
MalleshwaramUtkarsh, No. 49, 15th Cross, 8th Main Road, Malleshwaram, Bengaluru – 560003+91 90356 81163

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